Colorimetric Determination of Sildenafil Citrate (Viagra) Through Ion-Associate Complex Formation
نویسندگان
چکیده
منابع مشابه
Colorimetric determination of sildenafil citrate (Viagra) through ion-associate complex formation.
A simple, quick, accurate, and sensitive colorimetric method is described for the determination of sildenafil citrate (SLD). The method is based on the reaction of SLD with Congo Red, Sudan II, and Gentian Violet in buffered aqueous solutions at pH 2.5, 6.5, and 11.0, respectively, to give highly colored soluble ion-associate complex species; the colored products are quantitated colorimetricall...
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INTRODUCTION Nimesulide is a relatively cyclo-oxygenase-2 (COX2) selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old to decrease the risk of hepatotoxicity. It may be used orall...
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O presente trabalho apresenta uma metodologia simples, rápida e de baixo custo para a determinação de citrato de sildenafila (SC) em formulações farmacêuticas de referência (Viagra) e em produtos similares, genéricos e manipulados, por amperometria de múltiplos pulsos em sistema FIA (análise por injeção em fluxo). O método consiste na aplicação de três pulsos de potencial (sequenciais) em funçã...
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OBJECTIVES To determine whether the response to the new oral medication, sildenafil citrate (Viagra), was influenced by the presence or absence of the neurovascular bundles, as recent reports on its success did not specify the efficacy of the drug in patients with erectile dysfunction after radical prostatectomy. METHODS Baseline and follow-up data from 28 healthy patients presenting with ere...
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Three rapid spectrophotometric methods were developed for the determination of sunitinib based on the formation of ion-pair complex in acidic medium with bromocresol purple, bromothymol blue, and bromophenol blue. The formed ion-pair complexes, extractable with chloroform, were measured at 422 nm for bromocresol purple, 425 nm for bromothymol blue and 427 nm for bromophenol blue. All these meth...
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ژورنال
عنوان ژورنال: Journal of AOAC INTERNATIONAL
سال: 2009
ISSN: 1060-3271,1944-7922
DOI: 10.1093/jaoac/92.1.125